Genetic polymorphism of opioid receptors and use of opioid substances by high school students of Cotonou and Parakou (Benin)

In Benin, schools become sometimes the hub for dealing and consuming psychoactive substances; opioids in particular. The objectives of this study are to identify risk factors related use investigate genetic polymorphism mu delta opioid receptors teenagers young adults who consume schools. To accomplish this, 453 students participated study; R diversity 3.6.1 software RStudio environment was used experience through ASSIST V3.0 scoring. SNPs A118G on OPRM gene (µ) T921C OPRD (d), were searched by PCR DNA extracts from peripheral blood individuals. We identified 54 regular users 399 non users. This begins most with consumption alcohol tobacco is facilitated proximity marshlands, kiosks, pubs near high colleges. aggressive advertisement combined relative socio-cultural tolerance just worsen behavioral deviance. found no difference SNP frequencies (d) genes between consumers non-consumers.